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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAH
All Species:
35.76
Human Site:
Y166
Identified Species:
60.51
UniProt:
P00439
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P00439
NP_000268.1
452
51862
Y166
K
Q
F
A
D
I
A
Y
N
Y
R
H
G
Q
P
Chimpanzee
Pan troglodytes
XP_001156860
452
51858
Y166
K
Q
F
A
D
I
A
Y
N
Y
R
H
G
Q
P
Rhesus Macaque
Macaca mulatta
Q2HZ26
490
56076
M199
K
Y
F
V
D
V
A
M
G
Y
K
Y
G
Q
P
Dog
Lupus familis
XP_532671
494
56287
F185
T
I
Q
E
L
D
R
F
A
N
Q
I
L
S
Y
Cat
Felis silvestris
Mouse
Mus musculus
P16331
453
51910
Y166
K
Q
F
A
D
I
A
Y
N
Y
R
H
G
Q
P
Rat
Rattus norvegicus
P04176
453
51803
Y166
K
Q
F
A
D
I
A
Y
N
Y
R
H
G
Q
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507458
568
65241
Y282
K
Q
F
A
D
I
A
Y
N
Y
R
H
G
Q
P
Chicken
Gallus gallus
P70080
445
51121
D160
A
M
N
Y
K
H
G
D
P
I
P
E
I
E
F
Frog
Xenopus laevis
Q92142
481
55388
M190
K
Y
F
A
D
V
A
M
S
Y
K
Y
G
D
P
Zebra Danio
Brachydanio rerio
NP_956845
449
51336
Y164
K
E
F
A
D
I
A
Y
N
Y
R
H
G
Q
P
Tiger Blowfish
Takifugu rubipres
NP_001027850
454
52112
Y168
K
E
F
A
D
I
A
Y
N
Y
R
H
G
Q
P
Fruit Fly
Dros. melanogaster
P17276
452
51642
Y165
K
Y
F
A
D
I
A
Y
N
Y
K
H
G
E
P
Honey Bee
Apis mellifera
XP_623300
463
53197
Y176
K
Y
F
A
D
I
A
Y
N
Y
K
H
G
Q
P
Nematode Worm
Caenorhab. elegans
P90925
457
52111
F166
K
F
F
A
D
I
A
F
N
F
K
H
G
D
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
50.6
84.8
N.A.
91.8
92
N.A.
71.4
54.4
52.1
73.8
69.3
61.2
58.5
55.3
N.A.
Protein Similarity:
100
100
66.3
87.2
N.A.
95.8
96.2
N.A.
75.6
69.4
68.4
83.6
81.5
75.8
73.4
71.7
N.A.
P-Site Identity:
100
100
53.3
0
N.A.
100
100
N.A.
100
0
53.3
93.3
93.3
80
86.6
60
N.A.
P-Site Similarity:
100
100
73.3
13.3
N.A.
100
100
N.A.
100
6.6
80
100
100
93.3
93.3
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
79
0
0
86
0
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
86
8
0
8
0
0
0
0
0
15
0
% D
% Glu:
0
15
0
8
0
0
0
0
0
0
0
8
0
15
0
% E
% Phe:
0
8
86
0
0
0
0
15
0
8
0
0
0
0
8
% F
% Gly:
0
0
0
0
0
0
8
0
8
0
0
0
86
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
72
0
0
0
% H
% Ile:
0
8
0
0
0
72
0
0
0
8
0
8
8
0
0
% I
% Lys:
86
0
0
0
8
0
0
0
0
0
36
0
0
0
8
% K
% Leu:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% L
% Met:
0
8
0
0
0
0
0
15
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
72
8
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
79
% P
% Gln:
0
36
8
0
0
0
0
0
0
0
8
0
0
65
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
0
50
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% S
% Thr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
8
0
15
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
29
0
8
0
0
0
65
0
79
0
15
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _